Publication:20161121154049

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Publication
URL http://www.ncbi.nlm.nih.gov/pubmed/25378328
Title MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

Authors Judith A. H. Wodke, Andreu Alibés, Luca Cozzuto, Antonio Hermoso, Eva Yus, Maria Lluch-Senar, Luis Serrano, Guglielmo Roma
Date 2015-01

Publisher Nucleic Acids Research
DOI 10.1093/nar/gku1105
Tag Databases, Genetic, Genome, Bacterial, Internet, Metabolome, Mycoplasma pneumoniae, Proteome, Systems Biology, Transcriptome



Abstract:
MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is an interesting model organisms for the development of systems biology approaches for unicellular organisms. Our database hosts a wealth of omics-scale datasets generated by hundreds of experimental and computational analyses. These include data obtained from gene expression profiling experiments, gene essentiality studies, protein abundance profiling, protein complex analysis, metabolic reactions and network modeling, cell growth experiments, comparative genomics and 3D tomography. In addition, the intuitive web interface provides access to several visualization and analysis tools as well as to different data search options. The availability and--even more relevant--the accessibility of properly structured and organized data are of up-most importance when aiming to understand the biology of an organism on a global scale. Therefore, MyMpn constitutes a unique and valuable new resource for the large systems biology and microbiology community.


Annotation The BioCore developed MyMpn database to host and analyze omics-data generated by the Design of Biological Systems Group (CRG) and collaborators at the EMBL and other institutions.
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