Difference between revisions of "Services"

Revision as of 15:26, 28 November 2012

We currently offer different types of services for internal and external users:

High-throughput data analysis of genomics, transcriptomics, epigenetics and proteomics datasets

Next-Gen data analysis. The unit has invested time and effort in establishing several pipelines dedicated to the analysis of Deep-sequencing data. Currently, the unit has experience analyzing different types of deep-sequencing data:

· Transcription factor binding site detection / motif discovery

· Analysis of histone modifications

· Identification of target genes

· Data Visualization

2) High-resolution nucleosome positioning

3) Detection of Chromosomal Interactions (5C)

· Differential expression at the gene and transcript level

· Detection of rare, or novel transcripts

· Identification of alternative splicing and report of isoform abundance

· microRNA / Small RNA analysis (profiling and discovery)

· De-novo transcriptome assembly

· Data visualization

5) Variation Detection

· SNP calling

· Indel calling

· Variation filtration

· Functional impact assessment

· Data visualization

· Downstream analysis for the interpretation of gene lists, including gene set enrichment, GO and pathway analysis, orthology prediction

Identification of functional elements in the genomes:
- Automatic gene annotation (including non-coding genes)
- Regulatory sequences: DNA motif analysis (novel and known)

@@ Line 35: / Line 35: @@
 :: · Functional impact assessment
 :: · Data visualization
-: 6) [[De novo genome assembly|De_novo_assembly_flowchart]]
+: 6) [[De_novo_assembly_flowchart|De novo genome assembly]]
 :: · Downstream analysis for the interpretation of gene lists, including gene set enrichment, GO and pathway analysis, orthology prediction